DG-CST - Revision history

Mauro at 15:54, 20 June 2007

Mauro — Wed, 20 Jun 2007 15:54:17 GMT

←Older revision		Revision as of 15:54, 20 June 2007
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-	The DG-CST (Disease Gene Conserved Sequence Tags) database is a collection of conserved sequence elements, identified by a systematic genomic sequence comparison between a set of human more than 1000 genes involved in the pathogenesis of genetic disorders and their murine counterparts. About 8% of analyzed genomic areas is conserved, surpisingly mostly located in introns or intergenic regions. ~~Each identified CST~~ have been ~~extensively annotated~~ (see below).	+	The DG-CST (Disease Gene Conserved Sequence Tags) database is a collection of conserved sequence elements, identified by a systematic genomic sequence comparison between a set of human more than 1000 genes involved in the pathogenesis of genetic disorders and their murine counterparts. About 8% of analyzed genomic areas is conserved, surpisingly mostly located in introns or intergenic regions. Extensive annotations have been also performed on each CST, aimed to identify any possible biological role which may explain such conservation (see below).

	===How to reach and use DG-CST===		===How to reach and use DG-CST===

Giovanni — Wed, 20 Jun 2007 15:46:11 GMT

Mauro — Wed, 20 Jun 2007 15:43:19 GMT

←Older revision		Revision as of 15:43, 20 June 2007
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-	The DG-CST (Disease Gene Conserved Sequence Tags) database is a collection of conserved sequence elements, identified by a systematic genomic sequence comparison between a set of human more than 1000 genes involved in the pathogenesis of genetic disorders and their murine counterparts. Each CST have been ~~also~~ extensively annotated (see below).	+	The DG-CST (Disease Gene Conserved Sequence Tags) database is a collection of conserved sequence elements, identified by a systematic genomic sequence comparison between a set of human more than 1000 genes involved in the pathogenesis of genetic disorders and their murine counterparts. About 8% of analyzed genomic areas is conserved, surpisingly mostly located in introns or intergenic regions. Each identified CST have been extensively annotated (see below).

	===How to reach and use DG-CST===		===How to reach and use DG-CST===

Giovanni — Wed, 20 Jun 2007 15:41:06 GMT

←Older revision		Revision as of 15:41, 20 June 2007
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	BLASTZ is available at http://bio.cse.psu.edu.		BLASTZ is available at http://bio.cse.psu.edu.
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		+	{{footer resDBs}}

Mauro — Wed, 20 Jun 2007 14:11:35 GMT

References

←Older revision		Revision as of 14:11, 20 June 2007
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	===References===		===References===
		+	Boccia A, Petrillo M, di Bernardo D, Guffanti A, Mignone F, Confalonieri S, Luzi L, Pesole G, Paolella G, Ballabio A, Banfi S. ''DG-CST (Disease Gene Conserved Sequence Tags), a database of human-mouse conserved elements associated to disease genes.'' '''Nucleic Acids Res.''' 2005, 33(Database issue):D505-10.

	BLASTZ is available at http://bio.cse.psu.edu.		BLASTZ is available at http://bio.cse.psu.edu.

Mauro — Wed, 20 Jun 2007 14:08:13 GMT

←Older revision		Revision as of 14:08, 20 June 2007
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-	The DG-CST (Disease Gene Conserved Sequence Tags) database is a collection of conserved sequence elements, identified by a systematic genomic sequence comparison between a set of human more than 1000 genes involved in the pathogenesis of genetic disorders and their murine counterparts.	+	The DG-CST (Disease Gene Conserved Sequence Tags) database is a collection of conserved sequence elements, identified by a systematic genomic sequence comparison between a set of human more than 1000 genes involved in the pathogenesis of genetic disorders and their murine counterparts. Each CST have been also extensively annotated (see below).

	===How to reach and use DG-CST===		===How to reach and use DG-CST===

Mauro — Wed, 20 Jun 2007 14:05:28 GMT

How to reach and use DG-CST

←Older revision		Revision as of 14:05, 20 June 2007
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	===How to reach and use DG-CST===		===How to reach and use DG-CST===

-	The database is available at http://dgcst.ceinge.unina.it, where it is possible to query and select CSTs respect to ~~their~~ sequence and annotations. A graphic browser allows direct visualization of the CSTs and related annotations within the context of the relative gene and its transcripts.	+	The database is available at http://dgcst.ceinge.unina.it, where it is possible to query and select CSTs respect to both sequence and annotations. A graphic browser allows direct visualization of the CSTs and related annotations within the context of the relative gene and its transcripts.

	[[Image:Dgcst.jpg\|center\|600px\|thumb\|DG-CST Graphic browser]]		[[Image:Dgcst.jpg\|center\|600px\|thumb\|DG-CST Graphic browser]]

Mauro — Wed, 20 Jun 2007 14:03:45 GMT

←Older revision		Revision as of 14:03, 20 June 2007
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	The database is available at http://dgcst.ceinge.unina.it, where it is possible to query and select CSTs respect to their sequence and annotations. A graphic browser allows direct visualization of the CSTs and related annotations within the context of the relative gene and its transcripts.		The database is available at http://dgcst.ceinge.unina.it, where it is possible to query and select CSTs respect to their sequence and annotations. A graphic browser allows direct visualization of the CSTs and related annotations within the context of the relative gene and its transcripts.

-	[[Image:Dgcst.jpg\|center\|600px\|DG-CST Graphic browser]]	+	[[Image:Dgcst.jpg\|center\|600px\|thumb\|DG-CST Graphic browser]]

	===Available annotations of CSTs===		===Available annotations of CSTs===

Mauro — Wed, 20 Jun 2007 14:02:38 GMT

←Older revision		Revision as of 14:02, 20 June 2007
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	The database is available at http://dgcst.ceinge.unina.it, where it is possible to query and select CSTs respect to their sequence and annotations. A graphic browser allows direct visualization of the CSTs and related annotations within the context of the relative gene and its transcripts.		The database is available at http://dgcst.ceinge.unina.it, where it is possible to query and select CSTs respect to their sequence and annotations. A graphic browser allows direct visualization of the CSTs and related annotations within the context of the relative gene and its transcripts.

-	[[Image:Dgcst.jpg\|center\|DG-CST Graphic browser]]	+	[[Image:Dgcst.jpg\|center\|600px\|DG-CST Graphic browser]]

	===Available annotations of CSTs===		===Available annotations of CSTs===

Mauro — Wed, 20 Jun 2007 14:02:14 GMT

←Older revision		Revision as of 14:02, 20 June 2007
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	===How to reach and use DG-CST===		===How to reach and use DG-CST===
-	~~[[Image:Dgcst.jpg\|right\|thumb\|350px\|DG-CST Graphic browser]]~~	+
	The database is available at http://dgcst.ceinge.unina.it, where it is possible to query and select CSTs respect to their sequence and annotations. A graphic browser allows direct visualization of the CSTs and related annotations within the context of the relative gene and its transcripts.		The database is available at http://dgcst.ceinge.unina.it, where it is possible to query and select CSTs respect to their sequence and annotations. A graphic browser allows direct visualization of the CSTs and related annotations within the context of the relative gene and its transcripts.
		+
		+	[[Image:Dgcst.jpg\|center\|DG-CST Graphic browser]]

	===Available annotations of CSTs===		===Available annotations of CSTs===