HMMER

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(New page: HMMER HMMER is a freely distributable implementation of profile HMM software for sequence analysis. === How to reach and use HMMER === :HMMER applications can be searched and launched fr...)
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===Available programs === ===Available programs ===
:HMMER available programs are: :HMMER available programs are:
-[http://bioinfo.ceinge.unina.it/tools/winterf/hmmalign.php hmmalign]''': Align multiple sequences to a profile HMM.+:*'''[http://bioinfo.ceinge.unina.it/tools/winterf/hmmalign.php hmmalign]''': Align multiple sequences to a profile HMM.
-[http://bioinfo.ceinge.unina.it/tools/winterf/hmmbuild.php hmmbuild]''': Build a profile HMM from a given multiple sequence alignment.+:*'''[http://bioinfo.ceinge.unina.it/tools/winterf/hmmbuild.php hmmbuild]''': Build a profile HMM from a given multiple sequence alignment.
-[http://bioinfo.ceinge.unina.it/tools/winterf/hmmcalibrate.php hmmcalibrate]''': Determine appropriate statistical significance parameters for a profile HMM prior to doing database searches.+:*'''[http://bioinfo.ceinge.unina.it/tools/winterf/hmmcalibrate.php hmmcalibrate]''': Determine appropriate statistical significance parameters for a profile HMM prior to doing database searches.
-[http://bioinfo.ceinge.unina.it/tools/winterf/hmmconvert.php hmmconvert]''': Convert HMMER profile HMMs to other formats, such as GCG profiles.+:*'''[http://bioinfo.ceinge.unina.it/tools/winterf/hmmconvert.php hmmconvert]''': Convert HMMER profile HMMs to other formats, such as GCG profiles.
-[http://bioinfo.ceinge.unina.it/tools/winterf/hmmemit.php hmmemit]''': Generate sequences probabilistically from a profile HMM.+:*'''[http://bioinfo.ceinge.unina.it/tools/winterf/hmmemit.php hmmemit]''': Generate sequences probabilistically from a profile HMM.
-[http://bioinfo.ceinge.unina.it/tools/winterf/hmmfetch.php hmmfetch]''': Retrieve an HMM from an HMM database+:*'''[http://bioinfo.ceinge.unina.it/tools/winterf/hmmfetch.php hmmfetch]''': Retrieve an HMM from an HMM database
-[http://bioinfo.ceinge.unina.it/tools/winterf/hmmindex.php hmmindex]''': Create a binary SSI index for an HMM database+:*'''[http://bioinfo.ceinge.unina.it/tools/winterf/hmmindex.php hmmindex]''': Create a binary SSI index for an HMM database
-[http://bioinfo.ceinge.unina.it/tools/winterf/hmmpfam.php hmmpfam]''': Search a profile HMM database with a sequence (i.e., annotate various kinds of domains in the query sequence).+:*'''[http://bioinfo.ceinge.unina.it/tools/winterf/hmmpfam.php hmmpfam]''': Search a profile HMM database with a sequence (i.e., annotate various kinds of domains in the query sequence).
-[http://bioinfo.ceinge.unina.it/tools/winterf/hmmsearch.php hmmsearch]''': Search a sequence database with a profile HMM (i.e., find additional homologues of a modeled family).+:*'''[http://bioinfo.ceinge.unina.it/tools/winterf/hmmsearch.php hmmsearch]''': Search a sequence database with a profile HMM (i.e., find additional homologues of a modeled family).
:The userguide of HMMER package is available [http://bioinfo.ceinge.unina.it/help/hmmer/ here] :The userguide of HMMER package is available [http://bioinfo.ceinge.unina.it/help/hmmer/ here]

Revision as of 18:50, 20 June 2007

HMMER HMMER is a freely distributable implementation of profile HMM software for sequence analysis.

How to reach and use HMMER

HMMER applications can be searched and launched from the Bioinfo website through the PROGsDB.
Most of HMMER applications can be directly launched by CAPRI.
In the VLS environment, the HMMER package is fully available for command line use in the directory /bioprogs/hmmer.

Available programs

HMMER available programs are:
  • hmmalign: Align multiple sequences to a profile HMM.
  • hmmbuild: Build a profile HMM from a given multiple sequence alignment.
  • hmmcalibrate: Determine appropriate statistical significance parameters for a profile HMM prior to doing database searches.
  • hmmconvert: Convert HMMER profile HMMs to other formats, such as GCG profiles.
  • hmmemit: Generate sequences probabilistically from a profile HMM.
  • hmmfetch: Retrieve an HMM from an HMM database
  • hmmindex: Create a binary SSI index for an HMM database
  • hmmpfam: Search a profile HMM database with a sequence (i.e., annotate various kinds of domains in the query sequence).
  • hmmsearch: Search a sequence database with a profile HMM (i.e., find additional homologues of a modeled family).
The userguide of HMMER package is available here


References

Rice P, Longden I and Bleasby A EMBOSS: The European Molecular Biology Open Software Suite Trends in Genetics, 2000, 16:276-277.
For more details about HMMER, visit the HMMER web site
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