Research DB
From Wiki CEINGE
Contents |
DG-CST
The DG-CST database is a collection of conserved sequence elements, identified by a systematic genomic sequence comparison between a set of human genes involved in the pathogenesis of genetic disorders and their murine counterparts.
Status: Currently the database collects about 1100 disease genes and 70000 CSTs.
KINWEB
Kinweb is a collection of protein kinases encoded in the human genome.
- The website provides:
- a comprehensive analysis of functional domains of each gene product;
- a prediction of secondary and tertiary structure motifs by using machine learning based programs;
- a collection of conserved sequence elements identified by comparative analysis of human kinase genes and their murine counterparts, useful to the identification of additional coding sequences, such as alternatively spliced exons, or other regulatory elements.
Status: Currently the database collects abouts 500 kinase genes and 30000 CSTs.
SLS
CFTR
In collaboration with G. Castaldo lab., it is a database collecting novel mutations found inside high conserved intronic sequences of the human CFTR gene, potentially involved in the cystic fibrosis phenotype.
Status: Under development. Currentely it collects about 6000 sequences.
