Research DB
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| Revision as of 19:27, 1 June 2007 (edit) Leandra (Talk | contribs) (New page: ==DG-CST== The DG-CST database is a collection of conserved sequence elements, identified by a systematic genomic sequence comparison between a set of human genes involved in the pathogene...) ← Previous diff |
Current revision (14:51, 8 January 2011) (edit) (undo) Angelo (Talk | contribs) |
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| - | + | *[[CV-DISEASE]]: A collection of annotated genomic variants, identified by deep sequencing technology, within over 200 genes potentially involved in human cardiomyopathies. | |
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| - | Status: Currently the database collects about 1100 disease genes and 70000 CSTs. | ||
| + | *[[CFTR]]: A database developed in a study in collaboration with the laboratory of G. Castaldo, which contains novel mutations found within highly conserved intronic sequences of the human CFTR gene, to test their involvement in the pathogenesis of the cystic fibrosis phenotype. | ||
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| - | + | *[[KINWEB]]: A collection of protein kinases encoded in the human genome. | |
| :The website provides: | :The website provides: | ||
| :*a comprehensive analysis of functional domains of each gene product; | :*a comprehensive analysis of functional domains of each gene product; | ||
| :*a prediction of secondary and tertiary structure motifs by using machine learning based programs; | :*a prediction of secondary and tertiary structure motifs by using machine learning based programs; | ||
| :*a collection of conserved sequence elements identified by comparative analysis of human kinase genes and their murine counterparts, useful to the identification of additional coding sequences, such as alternatively spliced exons, or other regulatory elements. | :*a collection of conserved sequence elements identified by comparative analysis of human kinase genes and their murine counterparts, useful to the identification of additional coding sequences, such as alternatively spliced exons, or other regulatory elements. | ||
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| - | Status: Currently the database collects abouts 500 kinase genes and 30000 CSTs. | ||
| - | + | *[[DG-CST]]: The DG-CST database is a collection of conserved sequence elements, identified by a systematic genomic sequence comparison between a set of human genes involved in the pathogenesis of genetic disorders and their murine counterparts. | |
| + | *[[EYEDIS]]: A database developed within a project for the analysis of a population of patients affected by Age-related Macular Degeneration (AMD). | ||
| - | == CFTR == | ||
| - | In collaboration with G. Castaldo lab., it is a database collecting novel mutations found inside high conserved intronic sequences of the human CFTR gene, potentially involved in the cystic fibrosis phenotype. | ||
| - | + | {{footer|footername=footer biotools}} | |
Current revision
- CV-DISEASE: A collection of annotated genomic variants, identified by deep sequencing technology, within over 200 genes potentially involved in human cardiomyopathies.
- CFTR: A database developed in a study in collaboration with the laboratory of G. Castaldo, which contains novel mutations found within highly conserved intronic sequences of the human CFTR gene, to test their involvement in the pathogenesis of the cystic fibrosis phenotype.
- KINWEB: A collection of protein kinases encoded in the human genome.
- The website provides:
- a comprehensive analysis of functional domains of each gene product;
- a prediction of secondary and tertiary structure motifs by using machine learning based programs;
- a collection of conserved sequence elements identified by comparative analysis of human kinase genes and their murine counterparts, useful to the identification of additional coding sequences, such as alternatively spliced exons, or other regulatory elements.
- DG-CST: The DG-CST database is a collection of conserved sequence elements, identified by a systematic genomic sequence comparison between a set of human genes involved in the pathogenesis of genetic disorders and their murine counterparts.
- EYEDIS: A database developed within a project for the analysis of a population of patients affected by Age-related Macular Degeneration (AMD).
