Research DB

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The DG-CST database is a collection of conserved sequence elements, identified by a systematic genomic sequence comparison between a set of human genes involved in the pathogenesis of genetic disorders and their murine counterparts.


Kinweb is a collection of protein kinases encoded in the human genome.
The website provides:
  • a comprehensive analysis of functional domains of each gene product;
  • a prediction of secondary and tertiary structure motifs by using machine learning based programs;
  • a collection of conserved sequence elements identified by comparative analysis of human kinase genes and their murine counterparts, useful to the identification of additional coding sequences, such as alternatively spliced exons, or other regulatory elements.




In collaboration with G. Castaldo lab., it is a database collecting novel mutations found inside high conserved intronic sequences of the human CFTR gene, potentially involved in the cystic fibrosis phenotype.



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