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SRS (Sequence Retrieval System) is installed locally (version and runs on the cluster server. It is used to manage about 70 of the most popular public biological databases (DBs), such as EMBL, UNIPROT, REFSEQ, ENTREZGENE, UNIGENE, PFAM, INTERPRO, PATHWAY, PDB and many others (see Databases). Databases produced in house are easily integrated into SRS, allowing researchers to compare and link local data with public ones. Many applications, such as those of the EMBOSS package, are integrated into SRS.

[edit] How to reach and use SRS

SRS is available directly from the Bioinfo website (look for Image:Srs.jpg) or at the address .
By using the SRS web interface, it is possible to query DBs by string and/or numerical words. The system, in fact, reads the text contained in all fields within the databases and creates the relative indices; these indices are scanned when queries are performed, allowing rapid retrieval of data which satisfy the search criteria. SRS also allows to create personal views of the data and to launch many applications directly from the web interface.
More details about SRS and how to use it are available here

[edit] The system

SRS, developed early at the European Bioinformatics Institute (EBI) and now by the Biowisdom company, is used by major research centres because it provides a single simples interface for accessing the biological DBs and creates links for multiple searches. Thus, data from various DBs can be compared with each other and with locally produced data. Researcher can also create personal projects and store, retrieve and further access all performed queries and relative results.

[edit] References

Etzold T, Ulyanov A and Argos P SRS: information retrieval system for molecular biology data banks. Methods Enzymol. 266:114-28 (1996)
The official public server of SRS is mantained at SRS@EBI

Bioinformatics: Bioinfo Services: Bioinfo tools: EMBOSS - PHYLIP - BLAST - SRS - ENSEMBL - CAPRI - PROGsDB
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